News and Events
SmartTots: Building Community and Advocating for Important Research
SmartTots pediatric anesthetic neurotoxicity thought leaders discuss the current status of the field and provide insights into the future of the research. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Finding Ways to Move Forward
Pediatric anesthetic neurotoxicity investigators discuss the state of the research and identify compelling ways to move the field forward. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Designing the Proper Study
Pediatric anesthetic neurotoxicity thought leaders ponder the feasibility of designing and conducting studies that successfully isolate the effects of anesthetics from the effects of the procedure or patient’s underlying condition. View on YouTube.
Pediatric Anesthetic Neurotoxicity: The Pre-Clinical Journey
Pediatric anesthetic neurotoxicity researchers discuss how pre-clinical studies are providing insight into the mechanisms of neurotoxicity, and the impact on the future of clinical studies. View on YouTube.
Panda Symposium
SmartTots – Perspectives from the Front Lines
Millions of children undergo surgery annually. Recent studies suggest there may be reason for concern. This video, featuring Dr. Dean Andropoulos, Dr. Peter Davis, and Dr. Caleb Ing, provides a summary as to why research is needed and the type that is needed.
Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood
Importance Exposure of young animals to commonly used anesthetics causes neurotoxicity including impaired neurocognitive function and abnormal behavior. The potential neurocognitive and behavioral effects of anesthesia exposure in young children are thus important to...
SmartTots responds to the release of the secondary outcomes of the GAS Trial
The GAS trial Andrew Davidson and colleagues’ GAS trial (Jan 16, p 239)1 reports outcomes that are different to those initially registered on ClinicalTrials.gov (NCT00756600). There was one prespecified primary outcome, the Wechsler Preschool and Primary Scale of...
SAFETOTS responds to the GAS Trial
Lancet Correspondence from Weiss M, Becke K, Hansen TG, Engelhardt T. This letter represents a consensus response study from the Safe Anesthesia For Every Tot (SAFETOTS) initiative which addresses the need for teaching, training, education, supervision, and research...
Concern grows around anesthesia effects on babies
Research suggests that general anesthesia can be harmful to infant brains. By using a local anesthetic administered by spinal, doctors at UVM Medical Center operated on 12-day-old Mira Barr who was awake, comfortable and even gets a little sleepy. UVM Medical Center...
Straight Talk MD Podcast
Does general anesthesia have any long-term effects on learning, memory, or behavior in infants and children? Dr. Paul Yost, the Past President of the California Society of Anesthesiologists, speaks to the public on Straight Talk MD and answers the question:...
The rise and fall of anaesthesia-related neurotoxicity and the immature developing human brain
EDITORIAL T. G. Hansen and P.-A. Lonnqvist Very few issues (if any) within paediatric anaesthesia have, during the past roughly 15 years, caused so much concern and emotional disturbances as a plethora of animal studies that repeatedly have shown that exposure to most...