News and Events
SmartTots: Building Community and Advocating for Important Research
SmartTots pediatric anesthetic neurotoxicity thought leaders discuss the current status of the field and provide insights into the future of the research. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Finding Ways to Move Forward
Pediatric anesthetic neurotoxicity investigators discuss the state of the research and identify compelling ways to move the field forward. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Designing the Proper Study
Pediatric anesthetic neurotoxicity thought leaders ponder the feasibility of designing and conducting studies that successfully isolate the effects of anesthetics from the effects of the procedure or patient’s underlying condition. View on YouTube.
Pediatric Anesthetic Neurotoxicity: The Pre-Clinical Journey
Pediatric anesthetic neurotoxicity researchers discuss how pre-clinical studies are providing insight into the mechanisms of neurotoxicity, and the impact on the future of clinical studies. View on YouTube.
Panda Symposium
SmartTots – Perspectives from the Front Lines
Millions of children undergo surgery annually. Recent studies suggest there may be reason for concern. This video, featuring Dr. Dean Andropoulos, Dr. Peter Davis, and Dr. Caleb Ing, provides a summary as to why research is needed and the type that is needed.
A Population-based Study Evaluating the Association between Surgery in Early Life and Child Development at Primary School Entry
Abstract Background: It is unclear whether exposure to surgery in early life has long-term adverse effects on child development. The authors aimed to investigate whether surgery in early childhood is associated with adverse effects on child development measured at...
Anesthetic Neurotoxicity Meets Big Data: Reasons to Be Cheerful?
FOR more than a decade, the possibility that exposure to anesthetics may be harmful to the developing human brain has intrigued anesthesiologists and the public alike. The urgent desire to create more clarity and the need to inform parents of young children who need...
AAP REPORT UPDATES SAFE PRACTICES WHEN SEDATING A PEDIATRIC PATIENT
More children undergo medical and dental procedures that require sedation than in prior decades, prompting the American Academy of Pediatrics to update recommendations that provide a safety net for pediatric patients. The clinical report, “Guidelines for Monitoring...
Is anesthesia bad for children’s brains?
by Ron Litman, DO, Medical Director of Institute for Safe Medication Practices I recently received a call from a father whose four-year-old daughter was scheduled to receive general anesthesia for a surgical procedure expected to last about two hours. He was concerned...
Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood
Importance Exposure of young animals to commonly used anesthetics causes neurotoxicity including impaired neurocognitive function and abnormal behavior. The potential neurocognitive and behavioral effects of anesthesia exposure in young children are thus important to...
SmartTots responds to the release of the secondary outcomes of the GAS Trial
The GAS trial Andrew Davidson and colleagues’ GAS trial (Jan 16, p 239)1 reports outcomes that are different to those initially registered on ClinicalTrials.gov (NCT00756600). There was one prespecified primary outcome, the Wechsler Preschool and Primary Scale of...