by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Purpose of review: This article reviews recent advances and controversies of developmental anesthesia neurotoxicity research with a special focus on the unanswered questions in the field both from clinical and preclinical perspectives. Recent...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Anesthesia-induced neurotoxicity is a set of unfavorable adverse effects on central or peripheral nervous systems associated with administration of anesthesia. Several animal model studies from the early 2000’s, from rodents to non-human primates, have shown that...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Study objective: Studies investigating associations between maternal epidural analgesia (MEA) and autism spectrum disorder (ASD) in the offspring are conflicting and lack prospective neurobehavioral follow-up assessments for autistic traits. We aim to...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Background: Multiple human studies have shown no significant long-term results of anesthesia exposure during early childhood compared to the general population; however, reports on short-term neurodevelopmental assessment before and after anesthesia exposure...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Pre-clinical experimental evidence, along with a plausible biological rational suggests that exposure of neonates and young children to anesthesia may harm brain development. However, the translational relevance of these observations remains unsolved. While a...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Over the past 20 years, hundreds of preclinical studies of the developing central nervous system have been published concluding that the common γ-aminobutryic acid and N-methyl-d-aspartate binding anesthetic agents cause neuroapoptosis and other forms of...
