News and Events
SmartTots: Building Community and Advocating for Important Research
SmartTots pediatric anesthetic neurotoxicity thought leaders discuss the current status of the field and provide insights into the future of the research. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Finding Ways to Move Forward
Pediatric anesthetic neurotoxicity investigators discuss the state of the research and identify compelling ways to move the field forward. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Designing the Proper Study
Pediatric anesthetic neurotoxicity thought leaders ponder the feasibility of designing and conducting studies that successfully isolate the effects of anesthetics from the effects of the procedure or patient’s underlying condition. View on YouTube.
Pediatric Anesthetic Neurotoxicity: The Pre-Clinical Journey
Pediatric anesthetic neurotoxicity researchers discuss how pre-clinical studies are providing insight into the mechanisms of neurotoxicity, and the impact on the future of clinical studies. View on YouTube.
Panda Symposium
SmartTots – Perspectives from the Front Lines
Millions of children undergo surgery annually. Recent studies suggest there may be reason for concern. This video, featuring Dr. Dean Andropoulos, Dr. Peter Davis, and Dr. Caleb Ing, provides a summary as to why research is needed and the type that is needed.
Recent Study Shows No Difference between General Anesthesia and Regional Anesthesia in Short Duration Surgery
Brief exposure to anesthetizing chemicals does not cause future neurological problems large study finds The Anesthesia Dilemma A recent study finds that brief exposure to anesthetizing chemicals does not cause future neurological problems. Early-life exposure to...
Inhaled Anesthesia, Apoptosis, and the Developing Retina: A Window into the Brain?
EDITORIAL Steven Roth, MD In this month’s issue of Anesthesia & Analgesia, Cheng et al.1 describe how isoflurane produces apoptosis in the retina in 7-day-old mouse pups. They found that exposure to 2% isoflurane for 1 hour resulted in apoptosis in cells in the...
SmartTots Releases Consensus Statement Regarding Anesthesia Safety in Young Children
San Francisco – October 13, 2015 – SmartTots today released an updated consensus statement that emphasizes a need for more research into the safety of anesthetics and sedatives administered to infants and young children under the age of 4. The statement was endorsed...
The Anesthesia Dilemma
Researchers are trying to determine if chemicals used to knock out young children during surgery can have long-term repercussions on memory and development By Dina Fine Maron on June 30, 2015 The game is a contemporary of the original Nintendo but it still appeals to...
Research and Grants
Research Priorities SmartTots acknowledges insufficient human data exist to determine whether anesthetics induce neurotoxicity in the developing brain. SmartTots is dedicating its initial research investigations to elucidating whether a signal suggesting anesthetics...
Is There Evidence for Long-Term Neurocognitive Effects of Sedatives
Pediatric Sedation Outside of the Operating Room: A Multispecialty International Collaboration, 2015. Soriano SG, Vutskits L Abstract The potential neurotoxic effects of drugs used for anesthesia and sedation have captured the attention of pediatric care providers. As...