News and Events
SmartTots: Building Community and Advocating for Important Research
SmartTots pediatric anesthetic neurotoxicity thought leaders discuss the current status of the field and provide insights into the future of the research. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Finding Ways to Move Forward
Pediatric anesthetic neurotoxicity investigators discuss the state of the research and identify compelling ways to move the field forward. View on YouTube.
Pediatric Anesthetic Neurotoxicity: Designing the Proper Study
Pediatric anesthetic neurotoxicity thought leaders ponder the feasibility of designing and conducting studies that successfully isolate the effects of anesthetics from the effects of the procedure or patient’s underlying condition. View on YouTube.
Pediatric Anesthetic Neurotoxicity: The Pre-Clinical Journey
Pediatric anesthetic neurotoxicity researchers discuss how pre-clinical studies are providing insight into the mechanisms of neurotoxicity, and the impact on the future of clinical studies. View on YouTube.
Panda Symposium
SmartTots – Perspectives from the Front Lines
Millions of children undergo surgery annually. Recent studies suggest there may be reason for concern. This video, featuring Dr. Dean Andropoulos, Dr. Peter Davis, and Dr. Caleb Ing, provides a summary as to why research is needed and the type that is needed.
Research and Grants
Research Priorities SmartTots acknowledges insufficient human data exist to determine whether anesthetics induce neurotoxicity in the developing brain. SmartTots is dedicating its initial research investigations to elucidating whether a signal suggesting anesthetics...
Is There Evidence for Long-Term Neurocognitive Effects of Sedatives
Pediatric Sedation Outside of the Operating Room: A Multispecialty International Collaboration, 2015. Soriano SG, Vutskits L Abstract The potential neurotoxic effects of drugs used for anesthesia and sedation have captured the attention of pediatric care providers. As...
Anesthetic-Related Neurotoxicity in Children – ASA Works in Close Cooperation With FDA and Others to Advance Research
SmartTots and FDA American Society of Anesthesiologists Article March 1, 2015 Volume 79, Number 3 Anesthetic-Related Neurotoxicity in Children – ASA Works in Close Cooperation With FDA and Others to Advance Research Randall P. Flick, M.D., M.P.H., Chair Committee on...
CDER Conversations: SmartTots
Talking with Bob Rappaport, former director, Division of Anesthesia, Analgesia, and Addiction Products, Office of New Drugs, Center for Drug Evaluation and Research, FDA. Dr. Rappaport retired from government service September, 2014. Scientific studies in young...