The possibility that exposure to general anesthetics during early life results in long-term impairment of neural function attracted considerable interest over the past decade. Extensive laboratory data suggest that administration of these drugs during critical stages of central nervous system development can lead to cell death, impaired neurogenesis, and synaptic growth as well as cognitive deficits. These observations are corroborated by several recent human epidemiological studies arguing that such cognitive impairment might also occur in humans.
- The Neurotoxicity of General Anesthetic Drugs: Emphasis on the Extremes of Age
- Physician Groups Respond to FDA Safety Communication
- FDA Drug Safety Communication: FDA review results in new warnings about using general anesthetics and sedation drugs in young children and pregnant women
- Job Search Announcement: Program Officer
- Current thinking regarding potential neurotoxicity of general anesthesia in infants