The development and refinement of practices for the safe administration of anesthesia to children is a major success story in modern medicine. During the past several decades, there have been significant improvements in safety standards, cardiopulmonary monitoring, delivery systems, and airway management specific to the pediatric patient undergoing anesthesia. Millions of children receive anesthesia each year for surgical, procedural, or diagnostic purposes, and the majority of these patients receive a general anesthetic.
- Neonatal general anesthesia causes lasting alterations in excitatory and inhibitory synaptic transmission in the ventrobasal thalamus of adolescent female rats
- Mild hypothermia ameliorates anesthesia toxicity in the neonatal macaque brain
- Using animal models to evaluate the functional consequences of anesthesia during early neurodevelopment
- microRNA‐124 attenuates isoflurane‐induced neurological deficits in neonatal rats via binding to EGR1
- Hemin treatment protects neonatal rats from sevoflurane-induced neurotoxicity via the phosphoinositide 3-kinase/Akt pathway