The effect of neonatal anesthesia and pain on the developing brain is of considerable clinical importance, but few studies have evaluated noxious surgical input to the infant brain under anesthesia. Herein, the authors tested the effect of increasing isoflurane concentration on spontaneous and evoked nociceptive activity in the somatosensory cortex of rats at different postnatal ages.
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- Perinatal and neonatal use of sedation and analgesia
- More than 3 hours and less than 3 years: Safety of anaesthetic procedures in infants less than 3 years old subjected to surgery for more the 3 hours
- Ionizing radiation from computed tomography versus anesthesia for magnetic resonance imaging in infants and children: patient safety considerations
- Pediatric Anesthesia Considerations for Interventional Radiology