The Sixth PANDA Symposium was held on April 14th and 15th, 2018. The 2-day symposium program included the following sessions: (1) Report of the Outcomes Workshop, September 2017, (2) Lessons learned: neuroimaging studies and neurodevelopmental outcome research, (3) Engaging stakeholders to promote safe anesthesia/sedation care in young children, (4) Outcomes research in vulnerable pediatric populations, (5) Developmental neurotoxicity research, 2018 and (6) Moderated poster sessions.
- Cell cycle activation contributes to isoflurane-induced neurotoxicity in the developing brain and the protective effect of CR8.
- Protective Effects of Xenon on Propofol-Induced Neurotoxicity in Human Neural Stem Cell-Derived Models.
- Neonatal exposure to propofol affects interneuron development in the piriform cortex and causes neurobehavioral deficits in adult mice.
- The expression of glucose transporters and mitochondrial division and fusion proteins in rats exposed to hypoxic preconditioning to attenuate propofol neurotoxicity.
- Inhibition of microRNA-375 ameliorated ketamine-induced neurotoxicity in human embryonic stem cell derived neurons.