Researchers at the Mayo Clinic in collaboration with the National Center for Toxicological Research (NCTR) are conducting a population-based study of long-term cognitive development in a large cohort of Rochester, MN children. The study compares performance of children with no anesthetic exposure to those with single or multiple exposures prior to age three years on an extensive battery of neurocognitive tests including the operant test battery (OTB). Researchers at NCTR and Arkansas Children’s Hospital are using the OTB to evaluate cognitive performance in both children and non-human primates.
- Pack your bags, we’re going to Montreal!
- Neurodevelopmental effects of anesthesia and environmental factors
- Role of environmental stressors in determining the developmental outcome of neonatal anesthesia
- Insufficient Astrocyte-Derived Brain-Derived Neurotrophic Factor Contributes to Propofol-Induced Neuron Death through Akt/Glycogen Synthase Kinase 3β/Mitochondrial Fission Pathway
- Early Developmental Exposure to General Anesthetic Agents in Primary Neuron Culture Disrupts Synapse Formation via Actions on the mTOR Pathway