Abstract

Reproducing scientific observations is the foundation of trusted discoveries. In clinical sciences, specific questions are repeatedly asked by a multitude of observational studies or trials, and the rigorous meta-analysis of these multicentre datasets leads us closer toward the application of evidence-based medicine in our patients. A similar approach is less frequently applied to basic and even translational research, where differences in experimental protocols used, species studied, and outcome measures reported make direct comparison of laboratory studies at best very difficult.

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