On Wednesday, December 14, the United States Food and Drug Administration (FDA) released a Drug Safety Communication warning that; “repeated or lengthy use of general anesthetic or sedation drugs during surgeries or procedures in children younger than three years of age or in pregnant women during the final trimester may affect development of children’s brains”. The FDA defined lengthy as greater than three hours of exposure.
The FDA further stated, “Consistent with animal studies, recent human studies suggest that a single, relatively short exposure to general anesthetic and sedation drugs in infants or toddlers is unlikely to have negative effects on behavior or learning. However, further research is needed to fully characterize how early life anesthetic exposure affects children’s brain development.”
The full text of the FDA Drug Safety Communication is available here.