The development and refinement of practices for the safe administration of anesthesia to children is a major success story in modern medicine. During the past several decades, there have been significant improvements in safety standards, cardiopulmonary monitoring, delivery systems, and airway management specific to the pediatric patient undergoing anesthesia. Millions of children receive anesthesia each year for surgical, procedural, or diagnostic purposes, and the majority of these patients receive a general anesthetic.
- Comparer Pommes et Oranges: Perils of Translating Rodent Studies to Human Outcomes
- Repeated sevoflurane exposures inhibit neurogenesis by inducing the upregulation of glutamate transporter 1 in astrocytes.
- The propofol-induced mitochondrial damage in fetal rat hippocampal neurons via the AMPK/P53 signaling pathway.
- Ketamine modulates neural stem cell differentiation by regulating TRPC3 expression through the GSK3β/β-catenin pathway.
- Sevoflurane induces microRNA-18a to delay rat neurodevelopment via suppression of the RUNX1/Wnt/β-catenin axis.