by SmartTots | Aug 30, 2016 | Research Articles
Abstract Verapamil is a Ca2 + channel blocker and is highly prescribed as an anti-anginal, antiarrhythmic and antihypertensive drug. Ketamine, an antagonist of the Ca2 +-permeable N-methyl-d-aspartate-type glutamate receptors, is a pediatric anesthetic. Previously we...
by SmartTots | Aug 30, 2016 | News
Newswise — Chicago – July 11, 2016 – Millions of children have surgery every year – for everything from tonsil removal to correction of a heart defect – and understandably parents are often anxious about their child’s safety and comfort. The American Society of...
by SmartTots | Aug 30, 2016 | Research Articles
Abstract Sevoflurane is generally considered a pro-apoptotic agent in the neonatal brain. However, recent studies have suggested that low levels of sevoflurane anesthesia may be neuroprotective and have a memory enhancing effect. The present study aimed to investigate...
by SmartTots | Aug 30, 2016 | Research Articles
Abstract Early postnatal anesthesia causes long-lasting learning and memory impairment in rodents, however, evidence for a specific neurotoxic effect on early synaptogenesis has not been demonstrated. Drebrin A is an actin binding protein whose localization in...
by SmartTots | Aug 30, 2016 | Research Articles
Abstract Propofol is one of the most widely used intravenous anesthetics. However, repeated exposure to propofol may cause neurodegeneration in the developing brain. Dexmedetomidine (Dex), an α2 adrenoceptor agonist, has been previously demonstrated to provide...
