by SmartTots | Aug 6, 2016 | News
FOR more than a decade, the possibility that exposure to anesthetics may be harmful to the developing human brain has intrigued anesthesiologists and the public alike. The urgent desire to create more clarity and the need to inform parents of young children who need...
by SmartTots | Aug 6, 2016 | Research Articles
Abstract Ketamine has been reported to cause neonatal neurotoxicity via a neuronal apoptosis mechanism; however, no in vivo research has reported whether ketamine could affect postnatal neurogenesis in the hippocampal dentate gyrus (DG). A growing number of...
by SmartTots | Aug 6, 2016 | Research Articles
Abstract Volatile anesthetics can cause neuronal and glial toxicity in the developing mammalian brain, as well as long-term defects in learning and memory. The goals of this study were to compare anesthetics using a clinically relevant exposure paradigm, and to assess...
by SmartTots | Jun 29, 2016 | News
More children undergo medical and dental procedures that require sedation than in prior decades, prompting the American Academy of Pediatrics to update recommendations that provide a safety net for pediatric patients. The clinical report, “Guidelines for Monitoring...
by SmartTots | Jun 28, 2016 | Research Articles
Abstract BACKGROUND: Changes in electroencephalography (EEG) voltage range are used to monitor the depth of anaesthesia, as well as predict outcome after hypoxia-ischaemia in neonates. Xenon is being investigated as a potential neuroprotectant after hypoxic-ischaemic...