by SmartTots | Feb 1, 2016 | Research Articles
Biomed Res Int. Tao G1, Xue Q1, Luo Y1, Li G2, Xia Y1, Yu B1. Abstract Demand is increasing for safer inhalational anesthetics for use in pediatric anesthesia. In this regard, researchers have debated whether isoflurane is more toxic to the developing brain than...
by SmartTots | Jan 26, 2016 | Research Articles
Paediatr Anaesth. Disma N1, Mondardini MC2, Terrando N3, Absalom AR4, Bilotta F5. Abstract Preclinical evidence suggests that anesthetic agents harm the developing brain thereby causing long-term neurocognitive impairments. It is not clear if these findings apply to...
by SmartTots | Jan 23, 2016 | Research Articles
Numerous animal studies have shown that all commonly used intravenous anaesthetic drugs and volatile agents may cause neuronal apoptosis following exposure in early life. Most studies have focussed on detecting increased apoptosis but their methods are not always...
by SmartTots | Jan 23, 2016 | Research Articles
Very preterm born neonates (24-32 weeks gestation) are exposed to stressful and painful procedures during neonatal intensive care. Analgesic and sedation therapies are essential, and opiates and benzodiazepines are commonly used. These medications may negatively...
by SmartTots | Jan 23, 2016 | Research Articles
Sevoflurane is a widely used anaesthetic agent, including in anaesthesia of children and infants. Recent studies indicated that the general anaesthesia might cause the cell apoptosis in the brain. This issue raises the concerns about the neuronal toxicity induced by...
