SmartTots
  • Home
  • About
    • Who We Are
    • FAQ
  • News
    • Newsletter Archive
  • Resources
    • Healthcare Professionals Resources
    • Advice for Parents and Caregivers
    • Clinical Research Articles
    • Preclinical Research Articles
    • Live Stream
    • Newsletter Archive
    • Presentation Videos
    • Research and Grants
    • FDA Drug Safety Communication
  • Donor Recognition
  • Contact
Select Page

Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

by SmartTots | Oct 24, 2015 | Research Articles

The Lancet Published online: October 24, 2015  Summary Background Preclinical data suggest that general anaesthetics affect brain development. There is mixed evidence from cohort studies that young children exposed to anaesthesia can have an increased risk of poor...

Anaesthetics, infants, and neurodevelopment: case closed?

by SmartTots | Oct 24, 2015 | Research Articles

The Lancet David O Warner, MD, Randall P Flick, MD Summary  Exposure of young animals, including non-human primates, to all anaesthetic and many sedative agents used in current clinical practice consistently produces neural injury.1,2 Findings of initial studies...

Neonatal MRI: Can We Reduce Anesthesia Exposure? A National Survey

by SmartTots | Oct 24, 2015 | Research Articles

Presented at ASA, October 24, 2015 Scott Lipson, M.D., Benjamin Heller, M.D. Icahn School of Medicine at Mount Sinai, New York, New York, United States  Background: There is increasing literature raising a possible link between anesthetic exposure to the developing...

Estimation and Analysis of Unnecessarily Early Procedures in Infants Younger than Six Month of Age in the United States

by SmartTots | Oct 24, 2015 | Research Articles

Presented at ASA, October 24, 2015 Lisa M. Einhorn, M.D., Jonathan C. Routh, M.D.,M.P.H., Nathaniel H. Greene, M.D. Duke University Medical Center, Durham, North Carolina, United States   Background: In 2007, the United States Food and Drug Administration Anesthetic...

Development of a Translational, Preclinical Piglet Model of Anesthesia-Induced Neurotoxicity Mechanisms in the Pediatric Population

by SmartTots | Oct 24, 2015 | Research Articles

Presented at ASA, October 24, 2015 Emmett E. Whitaker, M.D., Bruno Bissonnette, M.D., Joseph Tobias, M.D., Tanner L. Koppert, B.S., Fievos L Christofi, Ph.D. Nationwide Children’s Hospital, Columbus, Ohio , United States Background: The effect of anesthetics on...
« Older Entries
Next Entries »

Categories

  • Clinical Articles
  • Events
  • News
  • Preclinical Articles
  • Research Articles

Recent Posts

  • A Scoping Review of the Mechanisms Underlying Developmental Anesthetic Neurotoxicity
  • 2025 Annual Meeting, presented by the International Anesthesia Research Society (IARS) and the Society of Critical Care Anesthesiologists (SOCCA), March 20 – 23, 2025, Honolulu, HI
  • Exposure to Operative Anesthesia in Childhood and Subsequent Neurobehavioral Diagnoses: A Natural Experiment Using Appendectomy
  • Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN): a multicentre, open-label, randomised controlled phase 4 trial. Claire Elizabeth Wainwright, et al. June 2024
  • Columbia University Physician Scientist and SmartTots Investigator, Caleb Ing, MD, publishes new findings regarding prenatal exposure to general anesthesia and subsequent risk to the child.

About SmartTots

The SmartTots program is a multi-year collaborative effort designed to increase the safety of anesthetic and sedative drugs for the millions of children who undergo anesthesia and sedation each year.

Contact SmartTots

Phone: 415-296-6905
Fax: 415-296-6901

E-mail: [email protected]

Tax Information

SmartTots is a research initiative of the IARS, a 501 c (3) non-profit organization.

Federal Tax ID 34-0750348

GuideStar/Candid

Guidestar

View our Summary

  • Privacy Policy
  • Terms of Use
  • International Anesthesia Research Society
  • X

Designed by Elegant Themes | Powered by WordPress