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Identifying Children at Risk for Anesthetic Neurotoxicity

by SmartTots | Oct 24, 2015 | Research Articles

Presented as ASA, October 24, 2015 Jurgen C. De Graaff, M.D.,Ph.D., Gijs van Kerckhoven, M.D., Wietze Pasma, D.V.M., Leo Van Wolfswinkel, M.D.,Ph.D. Wilhelmina Children’s Hospital, UMC Utrecht, Utrecht, Netherlands Background: An increasing number of animal- and...

Inhaled Anesthesia, Apoptosis, and the Developing Retina: A Window into the Brain?

by SmartTots | Oct 22, 2015 | News

EDITORIAL Steven Roth, MD In this month’s issue of Anesthesia & Analgesia, Cheng et al.1 describe how isoflurane produces apoptosis in the retina in 7-day-old mouse pups. They found that exposure to 2% isoflurane for 1 hour resulted in apoptosis in cells in the...

Sedation and analgesia practices in neonatal intensive care units (EUROPAIN): results from a prospective cohort study

by SmartTots | Oct 16, 2015 | Research Articles

The Lancet, October 2015 Summary Background Neonates who are in pain or are stressed during care in the intensive care unit (ICU) are often given sedation or analgesia. We investigated the current use of sedation or analgesia in neonatal ICUs (NICUs) in European...

Neonatal anesthesia: how we manage our most vulnerable patients

by SmartTots | Oct 16, 2015 | Research Articles

Korean J Anesthesiol. 2015 Oct Si Ra Bang Abstract Neonates undergoing surgery are at higher risk than older children for anesthesia-related adverse events. During the perioperative period, the maintenance of optimal hemodynamics in these patients is challenging and...

SmartTots Releases Consensus Statement Regarding Anesthesia Safety in Young Children

by SmartTots | Oct 13, 2015 | News

San Francisco – October 13, 2015 – SmartTots today released an updated consensus statement that emphasizes a need for more research into the safety of anesthetics and sedatives administered to infants and young children under the age of 4.  The statement was endorsed...
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Recent Posts

  • A Scoping Review of the Mechanisms Underlying Developmental Anesthetic Neurotoxicity
  • 2025 Annual Meeting, presented by the International Anesthesia Research Society (IARS) and the Society of Critical Care Anesthesiologists (SOCCA), March 20 – 23, 2025, Honolulu, HI
  • Exposure to Operative Anesthesia in Childhood and Subsequent Neurobehavioral Diagnoses: A Natural Experiment Using Appendectomy
  • Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN): a multicentre, open-label, randomised controlled phase 4 trial. Claire Elizabeth Wainwright, et al. June 2024
  • Columbia University Physician Scientist and SmartTots Investigator, Caleb Ing, MD, publishes new findings regarding prenatal exposure to general anesthesia and subsequent risk to the child.

About SmartTots

The SmartTots program is a multi-year collaborative effort designed to increase the safety of anesthetic and sedative drugs for the millions of children who undergo anesthesia and sedation each year.

Contact SmartTots

Phone: 415-296-6905
Fax: 415-296-6901

E-mail: [email protected]

Tax Information

SmartTots is a research initiative of the IARS, a 501 c (3) non-profit organization.

Federal Tax ID 34-0750348

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