SmartTots
  • Home
  • About
    • Who We Are
    • FAQ
  • News
    • Newsletter Archive
  • Resources
    • Healthcare Professionals Resources
    • Advice for Parents and Caregivers
    • Clinical Research Articles
    • Preclinical Research Articles
    • Live Stream
    • Newsletter Archive
    • Presentation Videos
    • Research and Grants
    • FDA Drug Safety Communication
  • Donor Recognition
  • Contact
Select Page

Efficacy of rutin in inhibiting neuronal apoptosis and cognitive disturbances in sevoflurane or propofol exposed neonatal mice

by SmartTots | Aug 15, 2015 | Research Articles

Int J Clin Exp Med. 2015; 8(8): 14397–14409. Published online 2015 Aug 15. Abstract Sevoflurane and propofol are widely used in pediatric anesthesia. Neurotoxicity of sevoflurane and propofol in developing brain has been reported and these effects raise concerns on...

Age-dependency of sevoflurane-induced electroencephalogram dynamics in children

by SmartTots | Jul 22, 2015 | Research Articles

Abstract Background General anaesthesia induces highly structured oscillations in the electroencephalogram (EEG) in adults, but the anaesthesia-induced EEG in paediatric patients is less understood. Neural circuits undergo structural and functional transformations...

Propofol: A Review of its Role in Pediatric Anesthesia and Sedation

by SmartTots | Jul 16, 2015 | Research Articles

CNS Drugs, July 2015, Volume 29, Issue 7, pp 543-563 Abstract Propofol is an intravenous agent used commonly for the induction and maintenance of anesthesia, procedural, and critical care sedation in children. The mechanisms of action on the central nervous system...

Anesthetic use in newborn infants: the urgent need for rigorous evaluation

by SmartTots | Jul 16, 2015 | Research Articles

Pediatr Res. 2015 Jul Abstract Approximately 1.5 million neonates receive general anesthesia each year for a surgical procedure. Despite this being an essential practice, a number of recent studies now indicate that anesthetic exposure could cause toxicity and...

Neuroprotective properties of vitamin C on equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in high fat diet fed neonatal mice

by SmartTots | Jul 15, 2015 | Research Articles

Int J Clin Exp Med. 2015; 8(7): 10444–10458. Published online 2015 Jul 15. Abstract Obesity has been reported to be one of the significant contributors to various chronic disease conditions. Childhood obesity has been on an alarming increase over recent years leading...
« Older Entries
Next Entries »

Categories

  • Clinical Articles
  • Events
  • News
  • Preclinical Articles
  • Research Articles

Recent Posts

  • A Scoping Review of the Mechanisms Underlying Developmental Anesthetic Neurotoxicity
  • 2025 Annual Meeting, presented by the International Anesthesia Research Society (IARS) and the Society of Critical Care Anesthesiologists (SOCCA), March 20 – 23, 2025, Honolulu, HI
  • Exposure to Operative Anesthesia in Childhood and Subsequent Neurobehavioral Diagnoses: A Natural Experiment Using Appendectomy
  • Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN): a multicentre, open-label, randomised controlled phase 4 trial. Claire Elizabeth Wainwright, et al. June 2024
  • Columbia University Physician Scientist and SmartTots Investigator, Caleb Ing, MD, publishes new findings regarding prenatal exposure to general anesthesia and subsequent risk to the child.

About SmartTots

The SmartTots program is a multi-year collaborative effort designed to increase the safety of anesthetic and sedative drugs for the millions of children who undergo anesthesia and sedation each year.

Contact SmartTots

Phone: 415-296-6905
Fax: 415-296-6901

E-mail: [email protected]

Tax Information

SmartTots is a research initiative of the IARS, a 501 c (3) non-profit organization.

Federal Tax ID 34-0750348

GuideStar/Candid

Guidestar

View our Summary

  • Privacy Policy
  • Terms of Use
  • International Anesthesia Research Society
  • X

Designed by Elegant Themes | Powered by WordPress