by SmartTots | Nov 3, 2020 | Research Articles
Abstract Since their first use, anaesthetic agents have seen major advancements and are now an indispensable element of surgical procedures. Two of the most used volatile anaesthetics are Isoflurane and Sevoflurane. These have neuroprotective effects on adult brains...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract Background In neonatal mice, sevoflurane, inspired through the nasal cavity to act as anesthesia, triggers neuronal apoptosis, inflammation and oxidative injury that can hamper cognitive functions in the growth of the central nervous system in the later...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract The progress of modern medicine would be impossible without the use of general anesthetics (GAs). Despite advancements in refining anesthesia approaches, the effects of GAs are not fully reversible upon GA withdrawal. Neurocognitive deficiencies attributed to...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract Background Currently, numerous animal studies have shown that exposure to commonly used general anesthetics during pregnancy may cause neurocognitive impairment in the offspring. Reportedly, exposure to sevoflurane during mid-trimester of pregnancy can...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract Background Children who are exposed to anesthesia multiple times may undergo cognitive impairment during development. The underlying mechanism has been revealed as anesthesia-induced cognitive deficiency in young rodents and monkeys. However, the molecular...
