by SmartTots | Nov 3, 2020 | Research Articles
Abstract Over the past few years, despite the lack of approved pediatric labelling, dexmedetomidine’s (DEX) use has become more prevalent in pediatric clinical practice as well as in research trials. Its respiratory-sparing effects and bioavailability by various...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract During the past two decades, a vast number of studies done on rodents and nonhuman primates have implicated general anesthetic exposure of developing brains in producing neurotoxicity leading to various structural and functional neurological abnormalities...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract Background Anaesthesia is neurotoxic in developing primates. Retrospective clinical studies show a correlation between exposure to anaesthesia during infancy and the occurrence of learning disorders (LD). Prospective studies failed to detect any influence of...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract Exposure to general anesthesia has been reported to induce neurotoxicity, impair learning, memory, attention, motor functions, as well as affect behavior in adult rodents and nonhuman primates. Though many have speculated similar effects in humans, previous...
by SmartTots | Nov 3, 2020 | Research Articles
Abstract The question of whether or not anesthesia exposure in early childhood causes long term neurodevelopmental harm continues to attract attention. There is already good evidence in humans that surgery and anesthesia in early childhood is not associated with a...
