SmartTots
  • Home
  • About
    • Who We Are
    • FAQ
  • News
    • Newsletter Archive
  • Resources
    • Healthcare Professionals Resources
    • Advice for Parents and Caregivers
    • Clinical Research Articles
    • Preclinical Research Articles
    • Live Stream
    • Newsletter Archive
    • Presentation Videos
    • Research and Grants
    • FDA Drug Safety Communication
  • Donor Recognition
  • Contact
Select Page

Epidural analgesia, intrapartum hyperthermia, and neonatal brain injury: a systematic review and meta-analysis.

by SmartTots | May 1, 2021 | Research Articles

Abstract Background Epidural analgesia is associated with intrapartum hyperthermia, and chorioamnionitis is associated with neonatal brain injury. However, it is not known if epidural hyperthermia is associated with neonatal brain injury. This systematic review and...

Changes in Plasma Glial Fibrillary Acidic Protein in Children Receiving Sevoflurane Anesthesia: A Preliminary Randomized Trial.

by SmartTots | May 1, 2021 | Research Articles

Abstract We investigated changes in plasma glial fibrillary acidic protein concentration during sevoflurane anesthesia induction in children < 3 years old and determined the effect of co-administering dexmedetomidine. This preliminary randomized trial included 60...

Prediction of levobupivacaine concentrations in neonates and infants following neuraxial rescue blocks.

by SmartTots | May 1, 2021 | Research Articles

Abstract Aim Pharmacokinetic simulation was used to characterize levobupivacaine disposition after regional anesthetic rescue for failed spinal anesthesia in neonates and infants. Methods Population pharmacokinetics of levobupivacaine were estimated after spinal...

Anesthesia and the Developing Brain: A Review of Sevoflurane-induced Neurotoxicity in Pediatric Populations.

by SmartTots | May 1, 2021 | Research Articles

Abstract Purpose For over 150 years of anesthetic practice, it was believed that the effects of general anesthetics were temporary and not adverse. A growing number of studies over the past 2 decades, however, have identified structural and cognitive abnormalities,...

Effects of general anaesthesia during pregnancy on neurocognitive development of the fetus: a systematic review and meta-analysis.

by SmartTots | May 1, 2021 | Research Articles

Abstract Background The US Food and Drug Administration warned that exposure of pregnant women to general anaesthetics may impair fetal brain development. This review systematically evaluates the evidence underlying this warning. Methods PubMed, EMBASE, and Web of...
« Older Entries
Next Entries »

Categories

  • Clinical Articles
  • Events
  • News
  • Preclinical Articles
  • Research Articles

Recent Posts

  • A Scoping Review of the Mechanisms Underlying Developmental Anesthetic Neurotoxicity
  • 2025 Annual Meeting, presented by the International Anesthesia Research Society (IARS) and the Society of Critical Care Anesthesiologists (SOCCA), March 20 – 23, 2025, Honolulu, HI
  • Exposure to Operative Anesthesia in Childhood and Subsequent Neurobehavioral Diagnoses: A Natural Experiment Using Appendectomy
  • Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN): a multicentre, open-label, randomised controlled phase 4 trial. Claire Elizabeth Wainwright, et al. June 2024
  • Columbia University Physician Scientist and SmartTots Investigator, Caleb Ing, MD, publishes new findings regarding prenatal exposure to general anesthesia and subsequent risk to the child.

About SmartTots

The SmartTots program is a multi-year collaborative effort designed to increase the safety of anesthetic and sedative drugs for the millions of children who undergo anesthesia and sedation each year.

Contact SmartTots

Phone: 415-296-6905
Fax: 415-296-6901

E-mail: [email protected]

Tax Information

SmartTots is a research initiative of the IARS, a 501 c (3) non-profit organization.

Federal Tax ID 34-0750348

GuideStar/Candid

Guidestar

View our Summary

  • Privacy Policy
  • Terms of Use
  • International Anesthesia Research Society
  • X

Designed by Elegant Themes | Powered by WordPress