by SmartTots | Nov 3, 2019 | Research Articles
Abstract Infants who undergo surgical procedures in the first few months of life are at a higher risk of death or subsequent neurodevelopmental abnormalities. Although the pathogenesis of these outcomes is multifactorial, an understanding of the nature and...
by SmartTots | Nov 3, 2019 | Research Articles
Abstract Background: The 5-year survival for pediatric acute lymphoblastic leukemia (ALL) is greater than 90%. One late effect of pediatric ALL associated with numerous long-term difficulties is neurocognitive deficits. The experience at our institution, as well as...
by SmartTots | Sep 25, 2019 | Research Articles
The recommendations presented in this report are relevant to studies of postanesthetic cognitive deficits for most experimental models, whether they address the developing, adult or aged brain. Abstract The purpose of this article is to provide a succinct summary of...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract Sevoflurane is the most widely used anesthetic administered by inhalation. Exposure to sevoflurane can elicit learning deficits and abnormal cognitive disorder. In this study, we investigated the function of long noncoding RNA (lncRNA) Gm15621. Primary...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract Background: Sevoflurane has been extensively employed for induction and maintenance of general anesthesia. The effect of sevoflurane-induced apoptosis in developmental neurotoxicity has been appreciated for some time now, but the underlying mechanism of...
