by SmartTots | May 4, 2019 | Research Articles
Abstract Microglia cells, the resident macrophages of the central nervous system, are key actors for specific brain functions that are critical for development and health. Microglial reactivity and functions, even when immature, play a major role if the developing...
by SmartTots | May 4, 2019 | Research Articles
Abstract Neurodegeneration has been reported in young animals after exposure to all commonly used general anesthetic agents. The brain may be particularly vulnerable to anesthetic toxicity during peak synaptogenesis (in gestation and infancy). Human studies of...
by SmartTots | May 4, 2019 | Research Articles
Abstract Background It is not known whether the neurotoxicity produced by anaesthetics administered to young animals can also occur in children. Exposure of infant macaques to ketamine impairs performance in selected domains of the Operant Test Battery (OTB), which...
by SmartTots | Apr 9, 2019 | News
Participants of the recent SmartTots Workshop for Preclinical Research in Anesthetic Neurotoxicity. The workshop brought together a diverse, multi-disciplinary group of researchers in an effort to develop a common framework for pre-clinical studies. The overarching...
by SmartTots | Mar 31, 2019 | Events
May 20–22, 2019 Aurora, Colorado. For more information, click here.
