by SmartTots | Jul 19, 2018 | Research Articles
Abstract There is concern that clinical use of anesthetic drugs may cause neurotoxicity in the developing brain and subsequent abnormal neurobehavior. We therefore evaluated neurotoxic effects of inhalation anesthetics in the neonatal rat brain, using in vivo...
by SmartTots | Jul 19, 2018 | Research Articles
Abstract Anesthesia facilitates surgery in millions of young children every year. Structural brain abnormalities and functional impairment observed in animals has created substantial concerns among clinicians, parents, and government regulators. Clinical studies...
by SmartTots | Jul 19, 2018 | Research Articles
Abstract OBJECTIVE: To investigate the effect of sevoflurane on cognitive function and inflammatory response of children after general anesthesia at different times. PATIENTS AND METHODS: Ninety-three pediatric patients who underwent general anesthesia surgery were...
by SmartTots | Jul 19, 2018 | Research Articles
Abstract BACKGROUND: The search for agents that bring about faster induction and quicker recovery in the operating room have yielded numerous anesthetics whose mechanisms of action and potential toxic side effects remain unknown, especially in the young and aging...
by SmartTots | Jul 19, 2018 | Research Articles
Abstract PURPOSE OF REVIEW: Adverse long-term impact of general anesthesia on the developing brain is a widely discussed and controversial issue with potential public health relevance. The goal of this article is to give insights into the most recent experimental and...