by SmartTots | Dec 24, 2016 | Research Articles
Abstract General anaesthesia is usually considered to safely induce a reversible brain state allowing the performance of surgery under optimal conditions. An increasing number of clinical and experimental observations, however, suggest that anaesthetic drugs,...
by SmartTots | Dec 24, 2016 | Research Articles
Abstract Early life exposure to general anesthesia in preclinical studies has consistently led to permanent cognitive deficits later in life. However, the extent to which this finding is translatable to humans is the subject of much debate as the results from clinical...
by SmartTots | Dec 24, 2016 | Research Articles
Abstract The development and refinement of practices for the safe administration of anesthesia to children is a major success story in modern medicine. During the past several decades, there have been significant improvements in safety standards, cardiopulmonary...
by SmartTots | Nov 21, 2016 | Research Articles
Abstract INTRODUCTION: Although animal studies have consistently demonstrated long-term neurocognitive deficits following early anesthetic exposure under certain conditions, risk in human children remains unknown. Magnetic resonance imaging (MRI) in young patients...
by SmartTots | Nov 21, 2016 | Research Articles
Abstract BACKGROUND: Early postnatal exposure to general anesthetic agents causes a lasting impairment in learning and memory in animal models. One hypothesis to explain this finding is that exposure to anesthetic agents during critical points in neural development...
