by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Pre-clinical experimental evidence, along with a plausible biological rational suggests that exposure of neonates and young children to anesthesia may harm brain development. However, the translational relevance of these observations remains unsolved. While a...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Over the past 20 years, hundreds of preclinical studies of the developing central nervous system have been published concluding that the common γ-aminobutryic acid and N-methyl-d-aspartate binding anesthetic agents cause neuroapoptosis and other forms of...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Background: The neurotoxicity effects of anesthetic exposure on the developing brain have been one of the current research hotspots and numerous articles were published in the past decades. However, the quality and comparative information of these articles...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract The effect of multiple general anesthesia (mGA) procedures administered in early life is a critical theme and has led the Food and Drug Administration (FDA) to issue an alert. This systematic review seeks to explore the potential effects on neurodevelopment...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Over the past two decades there has been an increase in reports of attention deficit-hyperactivity disorder and perhaps autism spectrum disorder that appear to coincide with a substantial number of general anaesthesia interventions during early stages of...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Advances in the field of pediatric anesthesiology have enabled the performance of complex and life-saving procedures with minimal patient discomfort. However, preclinical studies over the past two decades have been reporting substantial neurotoxic potential...
