by SmartTots | Nov 2, 2022 | Preclinical Articles, Research Articles
Abstract Background: Sevoflurane is one of the most popular inhalational anesthetics during perioperative period but presenting neurotoxicity among pediatric and aged populations. Recent experiments in vivo and in vitro have indicated that ferroptosis may contribute...
by SmartTots | Nov 2, 2022 | Preclinical Articles, Research Articles
Abstract As one of the commonly used inhalation anesthetics in clinical practice, sevoflurane is currently widely applied in surgery for children and the elderly due to its safety and efficacy. However, the neurotoxicity and cognitive impairment induced by sevoflurane...
by SmartTots | Nov 2, 2022 | Preclinical Articles, Research Articles
Abstract Damage to hippocampus, cerebellum, and cortex associated with cognitive functions due to anesthetic-induced toxicity early in life may cause cognitive decline later. Aquaporin 4 (AQP4), a key protein in waste clearance pathway of brain, is involved in...
