by SmartTots | Nov 2, 2021 | Research Articles
Abstract Anaesthesia exposure to the developing nervous system causes neuroapoptosis and behavioural impairment in vertebrate models. Mechanistic understanding is limited, and target-based approaches are challenging. High-throughput methods may be an important...
by SmartTots | Nov 2, 2021 | Research Articles
Abstract The effects of general anesthetics on the developing brain have aroused much attention in recent years. Sevoflurane, a commonly used inhalation anesthetic especially in pediatric anesthesia, can induce developmental neurotoxicity. In this study, the...
by SmartTots | Nov 2, 2021 | Research Articles
Abstract Background: The aim of the study was to describe and contrast the brain development and outcome among very preterm infants that were and were not exposed to surgery requiring general anesthesia prior to term equivalent age (TEA). Methods: Preterm infants born...
by SmartTots | Nov 2, 2021 | Research Articles
Abstract Background: The frequency coupling characteristics in electroencephalogram (EEG) induced by anesthetics have been well studied in adults, but the investigation of the age-dependent cross frequency coupling features from children to adults is still lacking....
by SmartTots | Nov 2, 2021 | Research Articles
Abstract Background: To explore the association between cesarean section (CS) and risk of autism spectrum disorder (ASD), and evaluate the possible factors influencing this association. Methods: In total, 950 patients diagnosed with ASD and 764 healthy controls were...
by SmartTots | Nov 2, 2021 | Research Articles
Abstract Global developmental delay / intellectual disability are common pediatric conditions. Brain magnetic resonance imaging (MRI), although an important diagnostic tool in the evaluation of these patients, often requires general anesthesia. Recent literature...