by SmartTots | May 1, 2021 | Research Articles
Abstract We investigated changes in plasma glial fibrillary acidic protein concentration during sevoflurane anesthesia induction in children < 3 years old and determined the effect of co-administering dexmedetomidine. This preliminary randomized trial included 60...
by SmartTots | May 1, 2021 | Research Articles
Abstract Aim Pharmacokinetic simulation was used to characterize levobupivacaine disposition after regional anesthetic rescue for failed spinal anesthesia in neonates and infants. Methods Population pharmacokinetics of levobupivacaine were estimated after spinal...
by SmartTots | May 1, 2021 | Research Articles
Abstract Purpose For over 150 years of anesthetic practice, it was believed that the effects of general anesthetics were temporary and not adverse. A growing number of studies over the past 2 decades, however, have identified structural and cognitive abnormalities,...
by SmartTots | May 1, 2021 | Research Articles
Abstract Background The US Food and Drug Administration warned that exposure of pregnant women to general anaesthetics may impair fetal brain development. This review systematically evaluates the evidence underlying this warning. Methods PubMed, EMBASE, and Web of...
by SmartTots | May 1, 2021 | Research Articles
Abstract Background Dental procedures under general anesthesia (DGA) was found to improve the oral health-related quality of children’s life. However, some parents and pediatricians expressed concern about the neurotoxicity of general anesthesia. The purpose of this...
by SmartTots | May 1, 2021 | Research Articles
Abstract Background There are concerns regarding neurobehavioral changes in infants exposed to parenteral opioids during labor, yet long-term neurodevelopment remains unstudied. Objective We aimed to examine the association between parenteral opioids for labor...
