We were interested to read the study by Schneuer et al looking at whether anesthesia in young children impacts on subsequent developmental assessment or school performance, and applaud their efforts to further examine what is a very important question for anesthetists, surgeons and parents. We feel that the study adds to the growing body of evidence that unnecessary multiple or prolonged general anesthetics should be avoided in early life.
- Cell cycle activation contributes to isoflurane-induced neurotoxicity in the developing brain and the protective effect of CR8.
- Protective Effects of Xenon on Propofol-Induced Neurotoxicity in Human Neural Stem Cell-Derived Models.
- Neonatal exposure to propofol affects interneuron development in the piriform cortex and causes neurobehavioral deficits in adult mice.
- The expression of glucose transporters and mitochondrial division and fusion proteins in rats exposed to hypoxic preconditioning to attenuate propofol neurotoxicity.
- Inhibition of microRNA-375 ameliorated ketamine-induced neurotoxicity in human embryonic stem cell derived neurons.