Dexmedetomidine is an a2-adrenergic receptor agonist with an eight-fold greater affinity for the a2-adrenergic receptor than its sister drug clonidine. It is a sedative that is clear, colourless and tasteless and has been used in children for a number of years. Advantages of Dexmedetomidine over other agents used in paediatrics include: ease of administration; reduction in postoperative analgesic requirements; and reduction in postoperative nausea and vomiting (PONV).
Recent Posts
- 2024 Annual Meeting, presented by the International Anesthesia Research Society (IARS) and the Society of Critical Care Anesthesiologists (SOCCA), May 17-19, 2024, Seattle, WA
- Society for Pediatric Anesthesia (SPA) and the American Academy of Pediatrics (AAP), Pediatric Anesthesiology 2024, April 12-14, 2024, Anaheim, CA
- Duration of Fetoscopic Spina Bifida Repair Does Not Affect the Central Nervous System in Fetal Lambs.
- Melatonin attenuates sevoflurane-induced hippocampal damage and cognitive deficits in neonatal mice by suppressing CypD in parvalbumin neurons.
- Engeletin Ameliorates Sevoflurane-Induced Cognitive Impairment by Activating PPAR-Gamma in Neonatal Mice.