Recent studies by Ing and colleagues (Ing) address the association between surgery, general anesthesia, ADHD (attention deficit hyperactivity disorder), and other mental illnesses in young children. Frisch and colleagues (Frisch) raise a methodological issue and call on Ing to conduct additional analysis to correct bias due to underestimating the hazard ratio (HR) for circumcision in boys.

Read the Letter to the Editor here.
Frisch, Earp, & Van Howe.
Anesthesia & Analgesia March 2021

Ing responds to Frisch et al that classification for circumcised boys is “unexposed” based on prior studies and because most circumcisions are done without general anesthesia. This issue has limited impact on HR bias.

Read the Response here.
Ing, Wall, Olfson, & Li.
Anesthesia & Analgesia March 2021