The potential for long-term neurotoxic effects of anesthetics on the developing human brain has led to intensified research in this area. To date, the human evidence has been inconclusive, but a large body of animal evidence continues to demonstrate cause for concern. On April 14 and 15, 2018 the sixth biennial Pediatric Anesthesia and Neurodevelopmental Assessment (PANDA) study symposium was held at Morgan Stanley Children’s Hospital of New York. This symposium brought together clinicians and researchers and served as a platform to review preclinical and clinical data related to anesthesia and neurotoxicity in developing brains. The program participants included many active investigators in the field of anesthesia neurotoxicity as well as stakeholders from different backgrounds with the common interest of potential anesthetic neurotoxicity in children. The moderated poster session included presentations of preclinical animal research studies. These studies focused on defining the anesthetic-induced neurotoxicity phenotype, understanding the mechanism of injury and discovering potential inhibitors of neurotoxic effects.
Recent Posts
- 2024 Annual Meeting, presented by the International Anesthesia Research Society (IARS) and the Society of Critical Care Anesthesiologists (SOCCA), May 17-19, 2024, Seattle, WA
- Society for Pediatric Anesthesia (SPA) and the American Academy of Pediatrics (AAP), Pediatric Anesthesiology 2024, April 12-14, 2024, Anaheim, CA
- Duration of Fetoscopic Spina Bifida Repair Does Not Affect the Central Nervous System in Fetal Lambs.
- Melatonin attenuates sevoflurane-induced hippocampal damage and cognitive deficits in neonatal mice by suppressing CypD in parvalbumin neurons.
- Engeletin Ameliorates Sevoflurane-Induced Cognitive Impairment by Activating PPAR-Gamma in Neonatal Mice.