by SmartTots | Sep 25, 2019 | Research Articles
The recommendations presented in this report are relevant to studies of postanesthetic cognitive deficits for most experimental models, whether they address the developing, adult or aged brain. Abstract The purpose of this article is to provide a succinct summary of...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract Sevoflurane is the most widely used anesthetic administered by inhalation. Exposure to sevoflurane can elicit learning deficits and abnormal cognitive disorder. In this study, we investigated the function of long noncoding RNA (lncRNA) Gm15621. Primary...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract Background: Sevoflurane has been extensively employed for induction and maintenance of general anesthesia. The effect of sevoflurane-induced apoptosis in developmental neurotoxicity has been appreciated for some time now, but the underlying mechanism of...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract Background: Numerous experimental studies show that anesthetics are potentially toxic to the immature brain. Even though benzodiazepines are widely used in pediatric anesthesia and intensive care medicine, only a few studies examine the effects of these drugs...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract Sevoflurane is a widely used anesthetic. A series of recent studies have shown that exposure to sevoflurane at an early stage is a risk factor for the development of learning and memory dysfunction. Euxanthone is a xanthone derivative obtained from Polygala...
by SmartTots | Sep 15, 2019 | Research Articles
Abstract The present study investigated the influence of sevoflurane on the cytotoxicity of neural stem cells of rats and deoxyribonucleic acid (DNA) methylation, and analyzed the correlation between degree of methylation and neurotoxicity of sevoflurane. Ten healthy...
