by SmartTots | Mar 20, 2018 | Research Articles
Abstract SmartTots (http://smarttots.org/) represents a public–private partnership between the International Anesthesia Research Society and the US Food and Drug Administration. Over the past 7 years, SmartTots has worked in collaboration with various stakeholders to...
by SmartTots | Mar 20, 2018 | Research Articles
Few if any issues received more attention in the field of pediatric perioperative care over the past decade than developmental anesthesia neurotoxicity. While the possibility of a plausible association between anesthesia and postoperative personality changes in...
by SmartTots | Mar 2, 2018 | Research Articles
Background Advances in anesthesia and surgery enable children to receive anesthesia with relative safety. Recently, young age, prolonged, and multiple anesthetics have been highlighted as risk factors for poorer neurodevelopmental outcome, with neurotoxicity of...
by SmartTots | Mar 2, 2018 | Research Articles
Abstract PURPOSE: Data from animal experiments suggest that exposure to general anesthetics in early life inhibits neurogenesis and causes long-term memory deficit. Considering short operating times and the popularity of sevoflurane in pediatric anesthesia, it is...
by SmartTots | Mar 2, 2018 | Research Articles
Abstract A large number of studies have demonstrated that inhalation anesthetic isoflurane induced neural cell death by apoptosis in various cell and animal models. Emulsified isoflurane (EIso) is a new type of intravenous preparation of isoflurane that attracts...
by SmartTots | Mar 2, 2018 | Research Articles
Abstract Evidence suggests multiple anesthetics in early childhood may increase risk for neurodevelopmental injury. We evaluated proportions of children undergoing circumcision and myringotomy, concomitantly with or prior to circumcision, and compared costs between...
