by SmartTots | Jan 23, 2016 | Research Articles
We reported before that the minimal alveolar concentration (MAC) of isoflurane is decreased in complex I-deficient mice lacking the NDUFS4 subunit of the respiratory chain (RC) (1.55 and 0.81 % at postnatal (PN) 22–25 days and 1.68 and 0.65 % at PN 31–34 days for...
by SmartTots | Jan 18, 2016 | News
Does general anesthesia have any long-term effects on learning, memory, or behavior in infants and children? Dr. Paul Yost, the Past President of the California Society of Anesthesiologists, speaks to the public on Straight Talk MD and answers the question:...
by SmartTots | Jan 13, 2016 | Research Articles
The possibility that exposure to general anesthetics during early life results in long-term impairment of neural function attracted considerable interest over the past decade. Extensive laboratory data suggest that administration of these drugs during critical stages...
by SmartTots | Jan 9, 2016 | News
EDITORIAL T. G. Hansen and P.-A. Lonnqvist Very few issues (if any) within paediatric anaesthesia have, during the past roughly 15 years, caused so much concern and emotional disturbances as a plethora of animal studies that repeatedly have shown that exposure to most...
by SmartTots | Jan 8, 2016 | Research Articles
Andreas W. Loepke1,2 and Laszlo Vutskits3 Pediatric Anesthesia Animal research, as a means to advance biological and medical knowledge, dates back to Aristotle and Galen. A millennium and a half later, in 1865, Claude Bernard established blinded experiments in animals...
