by SmartTots | Apr 4, 2015 | Research Articles
J Neurosurg Anesthesiol, April 2015. Li J, Xiong M, Nadavaluru PR, Zuo W, Ye JH, Eloy JD, Bekker A. Abstract BACKGROUND: Anesthetic agents (eg, isoflurane, propofol) may cause neurodegeneration in the developing brains and impair animals’ learning ability....
by SmartTots | Apr 3, 2015 | Research Articles
Exp Neurol, April 2015. Lee JH, Zhang J, Wei L, Yu SP Abstract Each year, about six million children, including 1.5 million infants, in the United States undergo surgery with general anesthesia, often requiring repeated exposures. However, a crucial question remains...
by SmartTots | Apr 3, 2015 | Research Articles
Biochem Biophys Res Commun, April 2015. Ni C, Li Z, Qian M, Zhou Y, Wang J, Guo X. Abstract Calcineurin (CaN) over-activation constrains synaptic plasticity and memory formation. Upon CaN activation, NFAT imports into the nucleus and guides its downstream genes,...
by SmartTots | Apr 2, 2015 | Research Articles
Project: Long-Term Outcome of Single vs. Triple Anesthesia Exposure of Infant Monkeys Dr. Brambrink proposes using their newly established infant non-human primate (NHP) model to simulate the human condition of general anesthesia in a highly controlled environment...
by SmartTots | Apr 2, 2015 | Research Articles
Int J Dev Neurosci, April 2015. Osterop SF, Virtanen MA, Loepke JR, Joseph B, Loepke AW, Vutskits L Abstract BACKGROUND: Human epidemiological data suggest a link between anesthesia exposure in early postnatal life and subsequent lasting neurocognitive...