by SmartTots | Mar 13, 2020 | Research Articles
Abstract Purpose To evaluate the effects of sex on miRNA expression in the hippocampus after isoflurane anesthesia in a neonatal piglet model. Methods Six male and 6 female piglets, aged 3–5 days, were anesthetized with 2% isoflurane in room air for 3 h. Full...
by SmartTots | Mar 13, 2020 | Research Articles
Abstract Background: Anesthetics, such as isoflurane, sevoflurane, ketamine, and desflurane, are commonly used in clinics. Specifically, isoflurane is one of the most commonly used inhalational anesthetics, which can be used in surgery patients of all ages, including...
by SmartTots | Mar 13, 2020 | Research Articles
Abstract Background: Propofol is an intravenous drug commonly used in anesthesia procedures and intensive care in children. However, it also has neurotoxic effects on children. MicroRNA plays an important role in neurological diseases and neurotoxicity. Methods: In...
by SmartTots | Mar 13, 2020 | Research Articles
Abstract General anesthetic (GA) is used clinically to millions of young children each year to facilitate surgical procedures, relieve perioperative stress, and provide analgesia and amnesia. During recent years, there is a growing concern regarding a causal...
by SmartTots | Mar 13, 2020 | Research Articles
Abstract Every day children of all ages are sedated or anaesthetized for dental treatment both in the hospital and more commonly now in the dental office. The use of physical restraint for a dental procedure in a child has largely been replaced or significantly...