by SmartTots | Jan 4, 2019 | Research Articles
Abstract Ketamine, an FDA-approved N-methyl-D-aspartate (NMDA) receptor antagonist, is commonly used for general pediatric anesthesia. Accumulating evidence has indicated that prolonged exposure to ketamine induces widespread apoptotic cell death in the developing...
by SmartTots | Jan 4, 2019 | Research Articles
Abstract Although numerous studies have raised public concerns regarding the safety of anesthetics including sevoflurane in children, the biochemical mechanisms leading to anesthetics-induced neurotoxicity remain elusive. Moreover, potential biomarker(s) for early...
by SmartTots | Jan 4, 2019 | Research Articles
More than one million children under the age of five undergo surgery annually in the United States. The most common procedures are myringotomy tubes, tonsillectomy/adenoidectomy, hernia repairs, and circumcisions. Recently, the issue of anesthesia-related...
by SmartTots | Jan 4, 2019 | Research Articles
We were interested to read the study by Schneuer et al looking at whether anesthesia in young children impacts on subsequent developmental assessment or school performance, and applaud their efforts to further examine what is a very important question for...
by SmartTots | Jan 4, 2019 | Research Articles
Abstract BACKGROUND: Recent experimental studies suggest that currently used anesthetics have neurotoxic effects on young animals. Clinical studies are increasingly published about the effects of anesthesia on the long term outcome, providing contradictory results....
