by SmartTots | Nov 14, 2017 | Research Articles
Over the past decade, a large body of evidence has suggested that there may be an association between anesthesia exposure and neurocognitive deficits in children. The majority of data are derived from animal studies, but some human studies support an association...
by SmartTots | Nov 8, 2017 | Research Articles
Abstract PURPOSE OF REVIEW: The U.S. Federal Drug Administration (FDA) recently released a warning stating that ‘repeated or lengthy use of general anesthetic and sedation drugs during surgeries or procedures in children younger than 3 years or in pregnant women...
by SmartTots | Nov 8, 2017 | Research Articles
Abstract Anaesthetic and sedative drugs transiently disrupt normal neural activity to facilitate healthcare procedures in children, but they can also cause long-term brain injury in experimental animal models. The US Food and Drug Administration (FDA) has recently...
by SmartTots | Nov 8, 2017 | Research Articles
Abstract BACKGROUND: Animals exposed to anesthetics during specific age periods of brain development experience neurotoxicity, with neurodevelopmental changes subsequently observed during adulthood. The corresponding vulnerable age in children, however, is unknown....
by SmartTots | Nov 8, 2017 | Research Articles
Abstract BACKGROUND: The anaesthetic dose causing neurotoxicity in animals has been evaluated, but the relationship between duration of volatile anaesthetic (VA) exposure and neurodevelopment in children remains unclear. METHODS: Data were obtained from the Western...
