by SmartTots | May 16, 2017 | Research Articles
Abstract Introduction Neurotoxicity induced by early developmental exposure to volatile anesthetics is a characteristic of organisms across a wide range of species, extending from the nematode C. elegans to mammals. Prevention of anesthetic-induced neurotoxicity (AIN)...
by SmartTots | May 16, 2017 | Research Articles
Abstract The mechanism by which anesthetics might act on the developing brain in order to cause long term deficits remains incompletely understood. The hippocampus has been identified as a structure that is likely to be involved, as rodent models show numerous...
by SmartTots | May 16, 2017 | Research Articles
General anesthesia has been in clinical use for over two centuries. Nevertheless, while the field has achieved significant mastery over its clinical applications and protocols which allow for efficient delivery and sophisticated monitoring of our patients, significant...
by SmartTots | May 15, 2017 | Research Articles
Abstract Almost 30 years ago, the American Academy of Pediatrics Committee on Fetus and Newborn coauthored a policy statement strongly advocating for the use of anaesthesia in all neonates stating ‘local or systemic pharmacologic agents now available permit...