by SmartTots | Dec 26, 2016 | Research Articles
Abstract PURPOSE OF REVIEW: Numerous preclinical studies have shown that general anesthetics adversely influence the development of young brains. These adverse effects are dose-dependent occurring in specific stages of brain development. Histologic examinations show...
by SmartTots | Dec 26, 2016 | Research Articles
The development and refinement of practices for the safe administration of anesthesia to children is a major success story in modern medicine. During the past several decades, there have been significant improvements in safety standards, cardiopulmonary monitoring,...
by SmartTots | Dec 26, 2016 | Research Articles
Preclinical studies1- 3 in young animals have demonstrated neurodegeneration and subsequent neurocognitive impairment for virtually all clinically available general anesthetic drugs. However, comparative human studies on this issue are scarce and inconclusive. BUY...
by SmartTots | Dec 24, 2016 | Research Articles
Abstract Importance The results of preclinical studies suggest that anesthetic drugs administered to neonatal animals cause widespread neuronal apoptosis and later neurocognitive impairment. Adequately powered studies in the pediatric surgical population are scarce,...
by SmartTots | Dec 24, 2016 | Research Articles
Abstract Thousands of infants and children undergo complicated surgical procedures that require prolonged periods of anesthesia and/or sedation each year. A growing body of preclinical research suggests pediatric anesthetics are harmful to the developing brain; yet,...
