by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Abstract Spinal anesthesia (SA) in the child under two years old is an excellent option when undergoing short genitourinary procedures. The use of SA in this patient population can avoid the potential deleterious neurocognitive effects on the developing brain that...
by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Despite decades of research, the question of developmental anesthetic neurotoxicity remains unsettled and continues to divide the medical community and beyond. Additionally, it continues to remain unknown if there is a clinically relevant biologic gradient of...
by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Abstract Background: Children undergoing complex cardiac surgery are exposed to substantial cumulative doses of sedative medications and volatile anesthetics and are more frequently anesthetized with ketamine, compared with healthy children. This study hypothesized...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Purpose of review: This article reviews recent advances and controversies of developmental anesthesia neurotoxicity research with a special focus on the unanswered questions in the field both from clinical and preclinical perspectives. Recent...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Anesthesia-induced neurotoxicity is a set of unfavorable adverse effects on central or peripheral nervous systems associated with administration of anesthesia. Several animal model studies from the early 2000’s, from rodents to non-human primates, have shown that...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Study objective: Studies investigating associations between maternal epidural analgesia (MEA) and autism spectrum disorder (ASD) in the offspring are conflicting and lack prospective neurobehavioral follow-up assessments for autistic traits. We aim to...
