by SmartTots | Jul 25, 2024 | Clinical Articles, News, Research Articles
Using a Medicaid database from 2001 – 2018, researchers undertake an observational study that takes advantage of a natural experiment associated with appendicitis to determine whether anesthesia and surgery in childhood were specifically associated with...
by SmartTots | Jun 17, 2024 | Clinical Articles, News, Research Articles
Data gathered from the original Australasian Cystic Fibrosis Bronchoalveolar Lavage (ACFBAL) trial provided a unique, optimal opportunity to examine the long-term effects of multiple exposures to general anaesthesia in a randomised controlled trial setting. The...
by SmartTots | May 24, 2024 | Clinical Articles, News, Research Articles
The association between prenatal exposure to general anaesthesia for maternal surgery during pregnancy and subsequent risk of disruptive or internalising behavioural disorder diagnosis in the child has not been well-defined. Columbia researchers, led by Caleb Ing,...
by SmartTots | Mar 1, 2024 | Clinical Articles, News, Research Articles
Anesthesia makes painful or uncomfortable diagnostic and interventional health care procedures tolerable, however, it may also disrupt key cellular processes in neurons and glia, harm the developing brain, and thereby impair cognition and behavior in children. Many...
by SmartTots | Jan 4, 2024 | Preclinical Articles, Research Articles
Abstract Background: Prenatal spina bifida aperta repair improves neurologic outcomes yet comes with a significant risk of prematurity and uterine scar-related complications. To reduce such complications, different fetoscopic techniques, for example, with varying...
by SmartTots | Jan 4, 2024 | Preclinical Articles, Research Articles
Abstract Background: Sevoflurane, a commonly administered inhaled anesthetic, is found to induce synaptic and mitochondrial damage in neonatal mice. Mitochondrial membrane potential (MMP) changes, mediated by Cyclophilin D (CypD), are implicated in mitochondrial...