by SmartTots | Nov 3, 2023 | Preclinical Articles, Research Articles
Abstract Sevoflurane exposure during rapid brain development induces neuronal apoptosis and causes memory and cognitive deficits in neonatal mice. Exosomes that transfer genetic materials including long non-coding RNAs (lncRNAs) between cells play a critical role in...
by SmartTots | Nov 3, 2023 | Preclinical Articles, Research Articles
Abstract Background Clinical studies suggest that anaesthesia exposure early in life affects neurobehavioural development. We designed a non-human primate (NHP) study to evaluate cognitive, behavioural, and brain functional and structural alterations after isoflurane...
by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Abstract Purpose of review: To provide an overview of anesthetic techniques for innovative diagnostic and therapeutic epilepsy procedures performed on pediatric patients. Recent findings: Recent studies have been published on the anesthetic consideration for...
by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Abstract Inguinal hernia surgery is one of the most common electively performed surgeries in infants. The common nature of inguinal hernia combined with the high-risk population involving a predominance of preterm infants makes this a particular area of interest for...
by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Abstract Introduction: The potential adverse effects of prolonged exposure to anesthetics in pediatric patients with severe-to-profound sensorineural hearing loss remain unclear. This study aimed to examine whether early bilateral cochlear implantation involving...
by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
The possibility that anesthetic and sedative drugs may be neurotoxic to the developing brain is of widespread importance to patients, parents, and the clinicians who care for them. This paper discusses the animal studies that initially questioned the safety of...
