“A substitute shines brightly as a king until a king be by” Portia, Act 5, Scene 1, The Merchant of Venice, William Shakespeare. Nonhuman primates (NHPs) have been important surrogates for modeling human diseases. In the field of perioperative medicine, preclinical investigations involving NHP fostered anesthetic drug development and made major contributions to our understanding of clinically relevant processes, including neurodegenerative disorders, cardiopulmonary physiology, and toxicology. Due to their close homology with humans, NHPs are broadly considered ideal species to investigate biomedical interactions.
Vutskits & Soriano
Anesthesia & Analgesia June 2022