by SmartTots | Jul 11, 2020 | Research Articles
Abstract Studies in animal models have revealed that long exposures to anesthetics can induce apoptosis in the newborn and young developing brain. These effects have not been confirmed in humans because of the lack of a non-invasive, practical in vivo imaging tool...
by SmartTots | Jul 11, 2020 | Research Articles
Abstract Conflict arises when surgeons and anesthesiologists disagree about goals of care in perioperative settings. Collaboration is essential for safe, efficient, and effective care. Drawing on 2 pediatric cases that highlight risks of anesthetic exposure, this...
by SmartTots | Jul 11, 2020 | Research Articles
Abstract Background Emergence delirium, a manifestation of acute postoperative brain dysfunction, is frequently observed after pediatric anesthesia and has been associated with the use of sevoflurane. Both xenon and dexmedetomidine possess numerous desirable...
by SmartTots | Jul 11, 2020 | Research Articles
Dexmedetomidine is an a2-adrenergic receptor agonist with an eight-fold greater affinity for the a2-adrenergic receptor than its sister drug clonidine. It is a sedative that is clear, colourless and tasteless and has been used in children for a number of years....
by SmartTots | Jul 11, 2020 | Research Articles
Abstract Background Anesthetic regimens using dexmedetomidine and short acting opioids have been suggested as potential alternatives to sevoflurane‐based anesthesia in children. The primary aim of this study is to compare demographics, intraoperative characteristics,...