by SmartTots | May 13, 2020 | Research Articles
Abstract In a recent issue of the British Journal of Anaesthesia, Zuppa and colleagues reported a landmark pharmacokinetic analysis of the pharmacokinetics of dexmedetomidine in neonates and infants undergoing cardiopulmonary bypass. Although the use of...
by SmartTots | May 13, 2020 | Research Articles
Abstract Purpose To determine the relevance of the Food and Drug Administration (FDA) warning regarding general anesthesia (GA) in children under 3 years of age for procedures lasting longer than 3 h, by surgical specialty and for otolaryngology specifically. Methods...
by SmartTots | May 13, 2020 | Research Articles
Abstract Neurotoxicity is not rare and periodically severe and even life-threatening adverse effect (AE) of drugs belonging to many therapeutic groups. Manifestations of neurotoxicity are variable: disturbances of peripheral nervous system (ototoxicity and...
by SmartTots | May 13, 2020 | Research Articles
Abstract We would like to thank both Ing et al. and Drs. Williams and Sartorelli for their thoughtful comments on our recent Editorial, “GAS, PANDA, and MASK: No Evidence of Clinical Anesthetic Neurotoxicity!” We address their concerns in turn below. Developmental...
by SmartTots | May 13, 2020 | Research Articles
Abstract In their recent Editorial, Drs. Vutskits and Culley discuss the General Anesthesia or Awake-regional Anesthesia in Infancy (GAS), Pediatric Anesthesia Neurodevelopment Assessment (PANDA), and Mayo Anesthesia Safety in Kids (MASK) studies.1 These studies are...
