by SmartTots | Nov 3, 2023 | Clinical Articles, Research Articles
Abstract Background: Children undergoing complex cardiac surgery are exposed to substantial cumulative doses of sedative medications and volatile anesthetics and are more frequently anesthetized with ketamine, compared with healthy children. This study hypothesized...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Purpose of review: This article reviews recent advances and controversies of developmental anesthesia neurotoxicity research with a special focus on the unanswered questions in the field both from clinical and preclinical perspectives. Recent...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Anesthesia-induced neurotoxicity is a set of unfavorable adverse effects on central or peripheral nervous systems associated with administration of anesthesia. Several animal model studies from the early 2000’s, from rodents to non-human primates, have shown that...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Study objective: Studies investigating associations between maternal epidural analgesia (MEA) and autism spectrum disorder (ASD) in the offspring are conflicting and lack prospective neurobehavioral follow-up assessments for autistic traits. We aim to...
by SmartTots | Aug 31, 2023 | Clinical Articles, Research Articles
Abstract Background: Multiple human studies have shown no significant long-term results of anesthesia exposure during early childhood compared to the general population; however, reports on short-term neurodevelopmental assessment before and after anesthesia exposure...
by SmartTots | Jun 28, 2023 | Clinical Articles, Research Articles
Abstract Pre-clinical experimental evidence, along with a plausible biological rational suggests that exposure of neonates and young children to anesthesia may harm brain development. However, the translational relevance of these observations remains unsolved. While a...
