by SmartTots | Sep 10, 2017 | News
Medical research is fundamental to our health and economic prosperity! We at SmartTots are grateful that Congress has made medical research a national priority through supporting the National Institutes of Health (NIH) and passage of the 21st Century Cures Act. But,...
by SmartTots | Sep 8, 2017 | Research Articles
The potential risk to the brains of young children in relation to exposure to anesthesia remains undetermined and is a subject of contention. The answer may depend on how the question is posed—that is, the outcome measures used to define neurotoxicity. The issue is...
by SmartTots | Sep 8, 2017 | Research Articles
Abstract Propofol is a general anesthetic commonly used in pediatric clinical practices. Experimental findings demonstrate that anesthetics induce widespread apoptosis and cognitive decline in a developing brain. Although anesthesia-mediated neurotoxicity is the most...
by SmartTots | Sep 4, 2017 | Research Articles
Abstract Mitochondria are supposed to be involved in the early pathogenesis of general anesthesia (GA)-induced neurotoxicity and long-term cognitive deficits in developing brains. However, effective pharmacologic agents targeted on mitochondria during GA exposure are...
by SmartTots | Sep 4, 2017 | Research Articles
Abstract BACKGROUND: Thousands of infants and children are undergoing anesthesia around the world every day. But impacts of anesthetics on the developing neural system remain unclear yet. Previous evidence showed that anesthesia might affect the developing neural...
