by SmartTots | Sep 1, 2021 | Research Articles
Abstract Pediatric sedation and anesthesia techniques have plenty of difficulties and challenges. Data on the pharmacologic, electroencephalographic, and neurologic response to anesthesia at different brain development times are only partially known. New data in...
by SmartTots | Sep 1, 2021 | Research Articles
Abstract Aim To examine whether anesthesia exposure is associated with neurocognitive decline in pediatric medulloblastoma. Methods Patients were treated at St. Jude Children’s Research Hospital and completed ≥2 protocol-directed neurocognitive assessments (n =...
by SmartTots | Sep 1, 2021 | Research Articles
Abstract Millions of young children undergo surgery and anesthesia each year, yet there is a lack of scientific consensus about the safety of anesthesia exposure for the developing brain. Also poorly understood is parental anesthesia-related decision-making and how...
by SmartTots | Aug 26, 2021 | Research Articles
In 2016, the US Food and Drug Administration issued a Drug Safety Warning regarding general anesthesia and its use during pregnancy. In particular, the safety announcement required medication labels to describe the studies in young animals and pregnant animals that...
by SmartTots | Jul 1, 2021 | Research Articles
Researchers at the Mayo Clinic in collaboration with the National Center for Toxicological Research (NCTR) are conducting a population-based study of long-term cognitive development in a large cohort of Rochester, MN children. The study compares performance of...
by SmartTots | Jun 29, 2021 | Research Articles
Abstract Ketamine, a phencyclidine derivative and N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used as an anesthetic, analgesic, and sedative agent in daily pediatric practice. Experimental studies have suggested that early prenatal or postnatal exposure...
